About us

 History

Gene Analysis Service was founded in August 1998 and started its service activity in July 1999. To ensure the highest level of quality and service, our quality management system in accordance with DIN EN ISO 9001 was implemented in an early stage. The first external certification was in 2001.
With our molecular biological services like custom sequencing or RFLP analysis, we could convince a still growing number of local and international customers.

Fast medical mutation screening of the lung surfactant associated genes SP-A, SP-B and GM/CSF-R was one of our earliest services. Keeping track with the scientific development in this field, SP-C (since 2001) and ABCA3 screening (since 2005) followed.

Today our portfolio of molecular biological tests has been expanded by 11 screening tests for partly very rare genetic diseases like CADASIL, Pseudoxanthoma eleasticum or Juvenile Hyaline Fibromatosis.  

Presently, satisfied customers in more than 26 countries on 5 continents take advantage of our services.

 Focus

Our primary activity is the development of molecular biological methods for the quick analysis of genetic markers in humans. We have specialized in rare hereditary diseases that require selected exon sequencing or complete gene mutation screening.

Whether during the development of new genetic tests or in setting up of custom genetic tests, we consider it important to keep in contact with clinical professionals and scientists in the field.


We offer our clients a complete, competent and flexible service, from the isolation of nucleic acids and the specific amplification of DNA fragments, to the ready-to-publish DNA sequence.

 Our facilities

Our laboratory is located in the southern district Tempelhof-Schöneberg of Berlin, Germany. Urgent medical diagnostic services are available 7 days a week.

 Our quality management system

To ensure the highest levels of quality and service, our work is subject to stringent internal and external controls. Our quality management system is in accordance with DIN EN ISO 9001.

 Our founder

Dr. Alfred C. Looman, a molecular biologist and biochemist has extensive basic and applied research experience including gene technology, microbiology and biotechnology.
After graduating in biology with focus on biochemistry and genetics at the
State University of Leiden, postgraduate studies at the Berlin Max-Planck-Institute for Molecular Genetics and the PhD study at the Dept. of Biochemistry of the Leiden University extended the basic scientific experience.
Post-doctoral research projects in the field of applied yeast biotechnology and human molecular biology led the way to the founding of a molecular biological service company:

  • (1985-1993) “Foreign expression of proteins in yeast”. Hüls Chemie Forschungsgesellschaft, Berlin.(1994-1998) “Molecular biology of lung surfactant proteins”. Dept. of Neonatology, Charité University Hospital, Berlin.

 He is president and managing director of Gene Analysis Service GmbH since 1998.
 
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