Research and Development
 Custom gene analysis: SNP and mutation screening by DNA sequencing
Since the completion of the Human Genome Project in the year 20011) and the publication of the results, it is possible to screen most human genomic sequences for mutations and polymorphisms.

Sequence comparison of patient and control groups often supplies information on those changes in the genomic DNA that cause a disease or a disposition to disease.

We provide custom genetic analysis of human DNA. On the basis of published sequences, we develop and optimize amplification protocols, isolate and sequence the amplified fragments to perform the sequence comparison with the published GenBank data 2) .

The results of the genetic analysis, and the methods developed are at the unlimited disposal of our clients. As sample material we can use genomic DNA, blood, tissue and preserved patient samples. 
Please note that the patient's informed consent for the genetic analysis of his DNA and, in case of research projects, the consent of the university institute's ethical commission is obligatory. The costs of the development of a custom gene screening depend on the amount and the size of the gene fragments and the number of samples to be analyzed.

Please contact us for an initial project evaluation and price offer.

1) The International Human Genome Sequencing Consortium (2001) The human genome Nature 409: 813-958

 Rapid detection and typing of Ureaplasma urealyticum
This bacterium is thought to be involved in chronic lung disease and in bronchopulmonary dysplasia (BPD) in premature infants.

The amplification of ribosomal DNA gene fragments and subsequent sequencing. E.g. to identify unknown bacterial contaminations in biological products. Ribotyping for the systematic characterization of plant species.

 Customer requests
For special requests, like development of a protocol for amplification of a specific gene, please do contact us

Use our experience and infrastructure to speed up your research!
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