| Since
the completion of the Human Genome Project in the year 20011)
and the publication of the results, it is possible to screen
most human genomic sequences for mutations and polymorphisms.
Sequence comparison of patient
and control groups often supplies information on those changes
in the genomic DNA that cause a disease or a disposition to
disease.
We provide custom genetic
analysis of human DNA. On the basis of published sequences, we
develop and optimize amplification protocols, isolate and
sequence the amplified fragments to perform the sequence
comparison with the published GenBank data 2) .
The results of the genetic
analysis, and the methods developed are at the unlimited
disposal of our clients.
As sample material we can use
genomic DNA, blood, tissue and preserved patient samples.
Please note that the patient's informed consent for the genetic
analysis of his DNA and, in case of research projects, the
consent of the university institute's ethical commission is
obligatory.
The costs of the development of a
custom gene screening depend on the amount and the size of the
gene fragments and the number of samples to be analyzed.
Please contact
us for an initial project evaluation and price offer.
1)
The International Human Genome Sequencing Consortium (2001) The
human genome Nature 409: 813-958
2) http://www.ncbi.nih.gov/Genbank/
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